Phosphaturic mesenchymal tumors (PMTs) are rare tumors commonly arising in soft tissues and bones. They are the main cause of tumor-induced osteomalacia (TIO), a paraneoplastic syndrome caused by production of FGF23 and other phosphatonins. “Non-phosphaturic” variant of PMTs (i.e., not associated with TIO) have been also reported. We describe a patient with a PMT of the middle ear, a very rare site for PMTs, in which TIO failed to develop although three phosphatonins were expressed.
"Non-phosphaturic" variant of phosphaturic mesenchymal tumor of the middle ear expressing multiple phosphatonins / Palmisano, Biagio; Pace, Annalisa; Colangelo, Luciano; Polimeni, Roberta; Sonato, Chiara; Messineo, Daniela; Minisola, Salvatore; Magliulo, Giuseppe; Riminucci, Mara; Corsi, Alessandro. - In: EAR, NOSE & THROAT JOURNAL. - ISSN 1942-7522. - (2023). [10.1177/01455613221149635]
"Non-phosphaturic" variant of phosphaturic mesenchymal tumor of the middle ear expressing multiple phosphatonins
Palmisano, BiagioCo-primo
Methodology
;Pace, AnnalisaCo-primo
;Colangelo, LucianoCo-primo
Conceptualization
;Polimeni, Roberta;Sonato, Chiara;Messineo, Daniela;Minisola, Salvatore;Magliulo, Giuseppe;Riminucci, MaraPenultimo
;Corsi, Alessandro
Ultimo
Conceptualization
2023
Abstract
Phosphaturic mesenchymal tumors (PMTs) are rare tumors commonly arising in soft tissues and bones. They are the main cause of tumor-induced osteomalacia (TIO), a paraneoplastic syndrome caused by production of FGF23 and other phosphatonins. “Non-phosphaturic” variant of PMTs (i.e., not associated with TIO) have been also reported. We describe a patient with a PMT of the middle ear, a very rare site for PMTs, in which TIO failed to develop although three phosphatonins were expressed.File | Dimensione | Formato | |
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